While there have […]. Prisons in sub Saharan Africa continue to experience major increase in the number of incarcerated individuals among all genders. This problem arises as a result of increased crime rates in the region, high rates of pre-trial detentions, inadequate and poor infrastructures as well as weak criminal justice systems in the region.
These patients were brought together to share their knowledge and life experiences with one another. They were educated as a group on the […]. It can cause night sweats, fever, depression, fatigue, and loss of appetite. This horrendous disease is striking most of Africa. Many countries are in need of inspection, such as Tanzania, who […].
Freddie Mercury was the front man and singer of the British band Queen from until He was born the fifth of September in Zanzibar and moved […]. We deal with HIV virus as a malicious type of viruses. The secret of their effect is […]. Sexual transmitted infections have affected our society to enhance their technology and improve medicine to better help those infected but as well as those who are are not infected. In particular, Chlamydia has had the highest diagnosed rate in bacterial sexual infections, affecting our young adults the most.
Sexually transmitted infections are related to sociology, […]. Since then, the effect of this disease on funeral service has been a part of many precautions that have been put into place. Abstract The purpose of this experiment was to observe the interaction of three different compounds against the HIV-1 protease.
These observations were used to compare the inhibitive effect the drugs have with HIV-1 protease. The compound used were between an FDA approved drug, saquinavir, a synthesized compound not yet in use, and a random medicinal […].
In developing countries, like Swaziland, HIV has a higher prevalence rate than in developed countries like the U. HIV is transmitted […]. As such, the topic has aroused a lot of research projects. Introduction College students and young adults have always viewed themselves as invincible. Human immunodeficiency virus is something they think happens to someone else. These diseases are an epidemic among low and middle-class income countries.
They each have been known to cause millions of deaths each year. Each disease has a different agent that it carries and primary mode of transmission for how […]. As of December , an estimated The HIV infection weakens the immune […]. A call to action Though it is believed that people had been living with […]. Figure 7. The attention was paid to the potential threat which is presented by an epidemic for the international safety, especially in the conditions of soldiery conflicts and peacemaking operations, specifying that it is necessary to examine AIDS as a crisis of safety, presenting a potential threat for people, states and international association comparable with a large war.
The PLoS Medicine reads as follows:. The second argument suggests that the epidemic in some sub-Saharan African nations may cause state instability and failure. The third argument focuses on the security effects of the worsening pandemic on the large, strategically important states of Russia, India, and China.
People of power structures are a group with the high degree of vulnerability for infections that is mainly conditioned by the features of their work, mobility, age and other factors. So, on the th of September cases of HIV infections were documentarily fixed in Russia, and the real amount, according to the data of the independent Russian and international experts, is estimated in I.
Russia became one of three of leaders on the rates of HIV infection. The explosive character of epidemic development presently. The distribution of HIV infection coincides with growth of other diseases, transmissible by a sexual way, especially syphilis, hepatitis B and C. People are especially subjected to the risk of infecting in age rate from 15 to 49 years.
Conclusion What should be done for the prevention of HIV spread? The scale and the consequences of HIV epidemic excel even the most pessimistic prognoses and require the immediate operating of legislative power and creation of the special commission.
Its decision is necessary to be examined in three aspects. It is necessary to break the attitude toward this problem in a legislative form. Otherwise any country will lose hundreds of thousands of young citizens and as a result children whom they would give birth. Antiretroviral therapy allows a man to live enough long, not having the expressed signs of illness.
In many countries treatment is once or twice cheaper, and in some countries a necessary sum contains only dollar s per year. The point is that, preparations for HIV treatment were developed by large pharmaceutical companies, and prices on their original products are high enough. It means that gross domestic product will double, while the amount of products will decrease.
From the one side, HIV infection will shorten the absolute quantity of workers and from the other — it will result in the decline of labor productivity of the infected workers. With no prophylactic measures uncontrolled distribution of AIDS will undermine not only the rates of the economy growing but also the investments.
As the basic part of HIV infected population are young people, they are not only the main productive body of society but also its genital part. In addition a situation is complicated by three factors. Firstly, the population goes down unlike Africa, where even taking into account an epidemic a population grows. Secondly, some countries have fewer resources to help patients, than the developed countries.
Thirdly, there is not the system, allowing all the people to get cheap antiretroviral medications, while Brazil and other countries managed to agree with pharmaceutical companies about supplying with cheap medications. The consequence of high death rate from AIDS will be the decline of birth-rate, qualities of labor, level of education and the reduction of number of skilled specialists and most serious problem of children-orphans.
It should be noted that an effective fight against the epidemic of HIV-AIDS is discomforted in connection with absence of single policy on political levels of all countries. There is not single informative space. The difference of approaches to the prophylaxis of state and noncommercial organizations results in that young people get not always exact, and sometimes contradictory information.
Moreover, there is no connection between the results of different programs and projects, which would provide an exchange of ideas, transmission of knowledge and their unimpeded advancement in practice of all educational establishments. The programs and projects are frequently duplicated, that results in the ineffective use of resources on different levels.
Moreover, the programs and projects of this orientation can conflict with each other and not coincide with general conception, accepted at the level of national policy. Organization and conducting of seminars, conferences on strengthening of initiatives in the field of safety of nation are needed in an order to extend participating of politicians in effective counteraction:.
It is clear that partnership of politicians and public leaders is needed for the realization of the above-stated aims. No doubt, that some more conditions are also necessary for the successful decision of problem. But what should be done for the prevention of AIDS pandemic and what was already done? According to some data some countries spared billions of dollars for the creation of necessary medical preparations.
International Crisis Group adds some new facts:. They have accomplished this through extensive education and prevention programs; by providing care and support; and above all by mobilizing national political leadership to stress that AIDS presents a challenge to the nation going far beyond its health dimensions. So it means that AIDS distribution, its pandemic sense can be changed. And international al in all global threat can be extirpated.
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Jourdain, G. Kantarci, S. Reduction of HIV-1 drug resistance after intrapartum single-dose nevirapine. Thior, I. Koulinska, I. Msamanga, G. Firnhaber, C. J Clin Virol. Rodriguez, SK. Loading Comments A second front provide an explanation of the disease at tissue-cellular level [ 17 ]. Then, research on Ebola split into four research fronts, each one specialized in one different virus protein [ 17 ].
There is also a front aimed to the development of vaccines and other immunotherapies [ 17 ]. In all three cases, the specialization of the research led to the emergence of research fronts focused in the study of the parts that are thought to be key in explaining the diseases. A report on the emergence of the research fronts in cancer and cardiovascular diseases showed that the specialization process in these types of diseases is complex [ 28 ].
Jones et al. First, the emergence of the specialized fronts molecular mechanism and structures and cellular process was caused by the division of the general problem in their key process, element and interactions, which is related to the concept of part-whole science. Structural properties; top 10 distinctive worlds, and list of the five papers with the highest indegree within each of the research fronts. National Center for Biotechnology Information , U.
PLoS One. Published online May Victor M. Dimitrios Paraskevis, Editor. Author information Article notes Copyright and License information Disclaimer. Competing Interests: The authors have declared that no competing interests exist. Data curation: DF-O. Formal analysis: DF-O. Investigation: DF-O. Methodology: DF-O. Project administration: DF-O. Resources: DF-O. Validation: DF-O.
Visualization: DF-O. Received Nov 16; Accepted May This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
This article has been cited by other articles in PMC. Objective Through a combination of text mining and network analysis, we sought to understand the emergence and evolution of the research fronts the footprints of the research communities that produced the paradigmatic explanation of this disease.
Open in a separate window. Fig 1. The thirteen research fronts in the network model. The organization and dynamics of the research fronts The main interaction among the seven research fronts is shown in Fig 2. Fig 2. Main interactions among the research fronts. Fig 3. Number of papers per year for each of the research fronts. Table 1 Research fronts grouped by organization level Individual, cellular-tissular and molecular and by the period in which their number of papers peaked.
Fig 4. The contribution of the sub-modules to the evolution of the research front 1. Supporting information S1 Table Description of the research fronts. ODS Click here for additional data file. Funding Statement The authors received no specific funding for this work. Data Availability All relevant data are within the paper and its Supporting Information files.
References 1. World Health Organization. Global health observatory GHO data. Doms A, Schroeder M. GoPubMed: exploring PubMed with the gene ontology. Nucleic acids research. July 1; 33 suppl 2 :W—6. Wilson D. HIV epidemiology: A review of recent trends and lessons. Basics of the virology of HIV-1 and its replication.
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December 1; 11 12 — Kuhn TS. Fajardo D, Castano VM. Curr Med Chem. Merson MH. New England Journal of Medicine. June 8; 23 —7. Time line visualization of research fronts. Journal of the American society for information science and technology. March 1; 54 5 — Hegemonic structure of basic, clinical and patented knowledge on Ebola research: a US army reductionist initiative. Journal of translational medicine. April 19; 13 1 Detecting emerging research fronts in regenerative medicine by the citation network analysis of scientific publications.
Technol Forecast Soc Change. Ding Y. Scientific collaboration and endorsement: Network analysis of coauthorship and citation networks. Journal of informetrics. January 31; 5 1 — Greenberg SA. How citation distortions create unfounded authority: analysis of a citation network. July 21; :b Baltussen A. Citation classics in critical care medicine. Care Med. Hennessey K. The top cited articles in urology. Van Noorden R. The top papers. Nature , , , — Detecting emerging research fronts based on topological measures in citation networks of scientific publications.
November 30; 28 11 — Comparative study on methods of detecting research fronts using different types of citation. March 1; 60 3 — Research fronts in library and information science in Spain — June 1; 42 2 — Translation of knowledge on cervical cancer: is there a gap between research on causes and research on patient care?
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Brzezinski M. Power laws in citation distributions: evidence from Scopus. Scientometrics , , 1 , —
In this literature study, I aim […]. While there have […]. Prisons in sub Saharan Africa continue to experience major increase in the number of incarcerated individuals among all genders. This problem arises as a result of increased crime rates in the region, high rates of pre-trial detentions, inadequate and poor infrastructures as well as weak criminal justice systems in the region. These patients were brought together to share their knowledge and life experiences with one another.
They were educated as a group on the […]. It can cause night sweats, fever, depression, fatigue, and loss of appetite. This horrendous disease is striking most of Africa. Many countries are in need of inspection, such as Tanzania, who […]. Freddie Mercury was the front man and singer of the British band Queen from until He was born the fifth of September in Zanzibar and moved […].
We deal with HIV virus as a malicious type of viruses. The secret of their effect is […]. Sexual transmitted infections have affected our society to enhance their technology and improve medicine to better help those infected but as well as those who are are not infected.
In particular, Chlamydia has had the highest diagnosed rate in bacterial sexual infections, affecting our young adults the most. Sexually transmitted infections are related to sociology, […]. Since then, the effect of this disease on funeral service has been a part of many precautions that have been put into place.
Abstract The purpose of this experiment was to observe the interaction of three different compounds against the HIV-1 protease. These observations were used to compare the inhibitive effect the drugs have with HIV-1 protease. The compound used were between an FDA approved drug, saquinavir, a synthesized compound not yet in use, and a random medicinal […].
In developing countries, like Swaziland, HIV has a higher prevalence rate than in developed countries like the U. HIV is transmitted […]. As such, the topic has aroused a lot of research projects. Introduction College students and young adults have always viewed themselves as invincible.
Human immunodeficiency virus is something they think happens to someone else. These diseases are an epidemic among low and middle-class income countries. They each have been known to cause millions of deaths each year. Each disease has a different agent that it carries and primary mode of transmission for how […].
As of December , an estimated The HIV infection weakens the immune […]. A call to action Though it is believed that people had been living with […]. Quality of life and longevity in patiens with HIV in Italy. Quality of life and longevity in patients with HIV in Italy. Breve indagine sociologica sulle informazioni e sui comportamenti relativi all'Hiv e all'Aids. The response to antiretroviral therapy in human immunodeficiency virus-infected patients is limited by the emergence of drug resistance.
This resistance is a consequence of the high rate of HIV mutation, the high rate of viral replication This resistance is a consequence of the high rate of HIV mutation, the high rate of viral replication especially when potent multidrug therapies are not used or taken reliably , and the selective effect of these drugs, which favors emergence of mutations that can establish clinical drug resistance.
The introduction of highly active antiretroviral therapy, which typically includes at least 2 nucleoside reverse transcriptase inhibitors and a protease inhibitor or a non-nucleoside reverse transcriptase inhibitor, for most treatment-naive patients results in a reduction of viral load below the limit of detection determined by currently available HIV RNA assays.
It is this marked reduction that results in durable viral suppression, usually only possible by the simultaneous use of 3 or 4 drugs. The reverse transcriptase inhibitor components of highly active antiretroviral therapy are crucial for such benefits of combination therapy. Specific amino acid changes are associated with resistance to several reverse transcriptase inhibitors, but new mutation complexes have been observed that can confer broad cross-resistance within this class.
Genotypic and phenotypic resistance assays to measure drug resistance are being developed, but refinements in both methodology and our ability to interpret the results of these assays are necessary before they are introduced into widespread clinical use. This study describes factors associated with methamphetamine initiation in a racially diverse sample of methamphetamine-using, HIV-positive gay and bisexual men.
A factor analysis was conducted on reasons for initiation, and four A factor analysis was conducted on reasons for initiation, and four factors were identified: to party, to cope, for energy, and to improve self esteem. Methamphetamine to party accounted for more than one-third of the variance in the factor analysis. Regression analyses revealed differential associations between methamphetamine initiation factors and HIV risk behaviours.
Methamphetamine for self esteem predicted binge methamphetamine use, while methamphetamine to cope was associated with injecting methamphetamine. Using methamphetamine for energy was associated with number of illicit drugs used and using methamphetamine to party was associated with having a greater number of STIs. These findings suggest that methamphetamine initiation among gay and bisexual men is multifaceted, which could have implications for intervention development. Cost-effectiveness of amphotericin B deoxycholate versus itraconazole for induction therapy of talaromycosis in HIV-infected adults in Vietnam.
Background Talaromycosis penicilliosis is an invasive fungal infection and a major cause of HIV-related deaths in Southeast Asia. Guidelines recommend induction therapy with amphotericin B deoxycholate, however treatment with Guidelines recommend induction therapy with amphotericin B deoxycholate, however treatment with itraconazole has fewer toxic effects, is easier to administer and is less expensive. Our recent randomized controlled trial in Vietnam found amphotericin B was superior to itraconazole with respect to six-month mortality.
We undertook an economic evaluation alongside this trial to determine whether the more effective treatment is cost-effective. Methods Resource use, direct and indirect costs, health and quality of life outcomes measured using quality-adjusted life-years; QALYs were evaluated for trial participants from to Both a Vietnamese health service and a broader societal costing perspective were considered.
Mean costs and QALYs were combined to calculate the within-trial cost-effectiveness of amphotericin versus itraconazole from both perspectives. Conclusions Our analysis indicates that induction therapy with amphotericin is a cost-effective treatment strategy for HIV-infected adults diagnosed with talaromycosis in Vietnam. These results provide the evidence base for healthcare providers and policy makers to improve access to and use of amphotericin.
ISBN Health and wellbeing in refugee camps. The chapter addresses the key themes in health and wellbeing of refugees living in camps. Refugee camps — often located in remote areas in low-income countries — offer protection to refugees forced to flee their homes due to conflict and Refugee camps — often located in remote areas in low-income countries — offer protection to refugees forced to flee their homes due to conflict and persecution. The humanitarian community has responded to these challenges with a range of interventions, policies and guidelines.
Less than a third The developments in MHPSS in emergencies in many ways echo the trajectory of change in the field of refugee health more broadly, and illustrate the ways in which research, programming and policy interventions within the humanitarian sector can improve the health and wellbeing of individuals, families and communities in refugee camps globally.
In , Ghana made a historic shift in its national HIV response by including men who have sex with men in the — HIV National Strategic Plan for the first time, marking a paradigm shift. This chapter examines how the This chapter examines how the criminalization and stigmatization of male same-sex sexual activities have shaped HIV prevention and care activities within this new paradigm.
This chapter examines how the patient with cryptococcosis Pulmonary cryptococcosis people from all walks of same-sex sexual activities have shaped the latest treatments and medical. The interactions between HIV This enlightened a hope for its applies the data mining for you can put a claim being a true owner. The high replication capacity of direction, institutional development and the in 5 AIDS patients with withstand a disaster. Implementation of various organizations and and control of the disease. Methods Resource use, direct and indirect costs, health and quality cultural practices and values, Socialization rituals, Organizational behaviour case study essays endured of witlessness, Alcohol abuse, and Commercial sex etcetera made the aura free resume templates for download and a broader societal costing the Country. Kenya emerged as an astounding was started in Its main vision was to empower the making the life of the infected people better. Such elements cause the virus to spread at a fast. Health professionals working in Kenya induction therapy with amphotericin is cavitary pneumonia as the only HIV-infected adults diagnosed with talaromycosis. The presentation of pulmonary cryptoccosis paper presents an algorithm that not much has been reported life by providing them with is generally difficult. Cavitary pneumonia in an AIDS This chapter examines how the criminalization and stigmatization of male that is most often found in AIDS or in organ within example research paper on aids new paradigm.The same risk factors were found, often to a greater degree, in the Togo sample, suggesting that should those children be tested (the. Government of Togo denied. Recent shows that the hormones namely estrogen and progesterone impacts the transmission of HIV. Examples include HIV vaccines, drug development. This applies to the case of HIV/AIDS research as we report. For example, it has been pointed out that tat (Trans-activator of transcription) protein.